(008) Suggestions for Modifications to the Female Sexual Function Index to be Inclusive of All Populations – Cognitive Interviews with Sexual and Gender Minority and Heterosexual Persons

Abstract Introduction Patient-reported outcome measures that were initially designed for research studies including heterosexual, partnered, educated cisgender women may have limited applicability clinical use among Sexual and Gender Minority (SGM) patients without a partner. Objective We aimed to conduct cognitive interviews with both SGM persons heterosexual determine readability, comprehension, of questionnaire items assess sexual function in populations diverse practices, focusing on from the Female Function Index (FSFI), establish content validity modified measure. Methods conducted four rounds 52 participants (28 SGM, 24 heterosexual) who provided feedback their comprehension wording FSFI response scales. Participants made recommendations changes questionnaire, which was iteratively revised between interview rounds. Two independent coders analyzed transcripts using structural coding based five predefined codes (i.e., satisfaction item, specificity/language change needed, missing/suggested patient definitions concepts, confusion item). Results After revisions found final version acceptable understandable, thereby reaching thematic saturation establishing FSFI. Modifications included: replacing all instances “sexual stimulation” “intercourse” activity (alone or partner)”; broadening definition “vaginal penetration” beyond penile-vaginal penetration; adding skip logic include option “no activity”. identified missing concepts important health, such as external lubricant. Heterosexual refined by be acceptable, offered targeted clarifying relevance certain domains (e.g., questions about “emotional closeness”), terminology sexually aroused (turned on) naturally lubricated (wet)) re-ordering “pain should asked earlier”). Conclusions Feedback direct supports modifying further psychometric testing. This other similar questionnaires need adapted broader practice population persons’ experiences are accurately reflected assessed, ultimately assuring health needs can met more inclusively. Further racially educationally is needed. Disclosure No